CBD Effects on Epilepsy Medication


It seems at least once a week I am asked about CBD Oil. It is showing promising results in the management of epilepsy. I have tried it briefly & my huMom believes it was helping me but we are hoping to get a specific CBD oil called, “Charlotte’s Web”, because it is made specifically to manage epilepsy. We are also doing our due diligence as this is a relatively new medication & it is not yet regulated (or legal) here in Canada.

A study is underway at the University of Alabama at Birmingham. Adults & children with hard to manage epilepsy are trying CBD oil but the study is also looking as to how CBD interacts with other seizure medications.

The study has found that there were significant changes in levels of the drugs clobazam, topiramate, & rufinamide in both adults & children. Changes in zonisamide & eslicarbazepine was observed in adults only. Except for clobazam, however, the drug levels did not change outside of the normally accepted range. Tests also showed that participants taking valproate & CBD showed slightly more stress on their liver.

The findings emphasize the importance of monitoring blood levels of anti epileptic drugs as well as liver function during treatment with CBD oil. The perception exists that since CBD is plant based, it is natural & safe. While this may be true, this study shows that CBD can interact with anti seizure drugs.

Studies like this are very helpful. We intend to try CBD Oil again, once we find a quality brand that clearly helps. There seems to be no question that CBD oil can shut down seizures but some standardization & quality control needs to be established. Maintaining a regular dosage is very important.

Do you use CBD Oil to manage epilepsy? If so, I’d like to hear your story.

CEO Olivia


Living With Canine Epilepsy


Olivia November 2015

It has happened more than once. My huMom tells someone that I live with canine epilepsy & they say something like, “If it was me, I’d have that dog put down”. People seem to think my life is nothing but suffering & endless seizures. Nothing could be further from the truth. 99.9% of the time, I’m just your average happy, playful dog with a keen sense of humor.

I do have special needs. I take three different medications twice a day, Potassium Bromide, Zonisamide & Phenobarbital, plus  my “cluster buster” Keppra when I do have a visit from the epi-monster. My huMom pays special attention to nutrition, food intake, & my supplements. She also tries to keep the home environment as stress free as possible with two dogs, a cat & a house pig.  My routine of daily exercise/walks are also important.

My huMom is also constantly researching & reaching out to other families with epi-dogs like me. Together we support one another & share information. I also have a wooftastic vet who regularly consults an animal neurologist on my behalf.

In short, I have a very good life. I’m loved & cared for. That being said, I know I’m one of the fortunate ones. Many epi-warriors have fallen to this disease. It is my hope that one day a cure is found.

CEO Olivia

My Cocktail


DOG labcoat

I need to take what we call a cocktail of medications every day. I take several anti-epileptic drugs (AED’s). Over time I’ve had to adjust my dosage or completely change a drug. Today I want to break down what I’m taking now & briefly describe what they do.

Potassium Bromide –  it’s actually the bromide salt that has anti-seizure properties. It is often the second drug of choice when it comes to controlling seizures with Phenobarbital being the first. It basically calms the nervous system.

Phenobarbital – is a barbiturate. It is the most commonly prescribed anti-epileptic drug  for dogs. It is considered safe & effective. It works by slowing down the brain & nervous system. For some dogs, Phenobarbital is all that’s needed to manage their epilepsy.

Zonisamide – is an anti-convulsant. It works much like Keppra in that it prevents brain cells from firing too quickly.

Keppra – Also known as levetiracetam, Keppra works by affecting the transmission of nerve signals in the brain. During a seizure it prevents brain cells from going haywire by keeping them “firing” at a normal rate. I take Keppra only when I’ve had an epileptic event. I call it my cluster buster.

There are many other AED’s. What works for some dogs may not work for another & some of these medications may lose their effectiveness over time. I’ve had to adjust or completely change a medication. I’m fortunate to have a vet who consults a neurologist regularly on my behalf. She also does a lot of research on canine epilepsy & keeps up to date on the latest information.

CEO Olivia